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BMCBI
2004
92views more  BMCBI 2004»
10 years 11 months ago
BioBuilder as a database development and functional annotation platform for proteins
Background: The explosion in biological information creates the need for databases that are easy to develop, easy to maintain and can be easily manipulated by annotators who are m...
J. Daniel Navarro, Naveen Talreja, Suraj Peri, B. ...
BMCBI
2004
229views more  BMCBI 2004»
10 years 11 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...
BMCBI
2004
125views more  BMCBI 2004»
10 years 11 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
BMCBI
2004
133views more  BMCBI 2004»
10 years 11 months ago
Esub8: A novel tool to predict protein subcellular localizations in eukaryotic organisms
Background: Subcellular localization of a new protein sequence is very important and fruitful for understanding its function. As the number of new genomes has dramatically increas...
Qinghua Cui, Tianzi Jiang, Bing Liu, Songde Ma
BMCBI
2004
108views more  BMCBI 2004»
10 years 11 months ago
Enhanced protein domain discovery using taxonomy
Background: It is well known that different species have different protein domain repertoires, and indeed that some protein domains are kingdom specific. This information has not ...
Lachlan James M. Coin, Alex Bateman, Richard Durbi...
BMCBI
2004
174views more  BMCBI 2004»
10 years 11 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
BMCBI
2004
111views more  BMCBI 2004»
10 years 11 months ago
The Hotdog fold: wrapping up a superfamily of thioesterases and dehydratases
Background: The Hotdog fold was initially identified in the structure of Escherichia coli FabA and subsequently in 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. strain CB...
Shane C. Dillon, Alex Bateman
MAGS
2007
168views more  MAGS 2007»
10 years 11 months ago
Agent-based protein structure prediction
A protein is identified by a finite sequence of amino acids, each of them chosen from a set of 20 elements. The Protein Structure Prediction Problem is the problem of predicting...
Luca Bortolussi, Agostino Dovier, Federico Fogolar...
JIB
2007
172views more  JIB 2007»
10 years 11 months ago
The ABC (Analysing Biomolecular Contacts)-database
As protein-protein interactions are one of the basic mechanisms in most cellular processes, it is desirable to understand the molecular details of protein-protein contacts and ult...
Peter Walter, Sam Ansari, Volkhard Helms
JCC
2007
131views more  JCC 2007»
10 years 11 months ago
An extended dead-end elimination algorithm to determine gap-free lists of low energy states
: Proteins are flexible systems and commonly populate several functionally important states. To understand protein function, these states and their energies have to be identified...
Edda Kloppmann, G. Matthias Ullmann, Torsten Becke...
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