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BMCBI
2005
150views more  BMCBI 2005»
13 years 4 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
BMCBI
2005
253views more  BMCBI 2005»
13 years 4 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
BMCBI
2005
77views more  BMCBI 2005»
13 years 4 months ago
Ontological visualization of protein-protein interactions
Background: Cellular processes require the interaction of many proteins across several cellular compartments. Determining the collective network of such interactions is an importa...
Harold J. Drabkin, Christopher Hollenbeck, David P...
BMCBI
2005
61views more  BMCBI 2005»
13 years 4 months ago
SeqX: a tool to detect, analyze and visualize residue co-locations in protein and nucleic acid structures
Background: The interacting residues of protein and nucleic acid sequences are close to each other
Jan C. Biro, Gergely Fördös
BMCBI
2005
95views more  BMCBI 2005»
13 years 4 months ago
Oligomeric protein structure networks: insights into protein-protein interactions
Background: Protein-protein association is essential for a variety of cellular processes and hence a large number of investigations are being carried out to understand the princip...
K. V. Brinda, Saraswathi Vishveshwara
BMCBI
2005
119views more  BMCBI 2005»
13 years 4 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
BIOINFORMATICS
2005
114views more  BIOINFORMATICS 2005»
13 years 4 months ago
Predicting protein localization in budding Yeast
Motivation: Most of the existing methods in predicting protein subcellular location were used to deal with the cases limited within the scope from two to five localizations, and o...
Kuo-Chen Chou, Yu-Dong Cai
TCBB
2008
138views more  TCBB 2008»
13 years 4 months ago
PairProSVM: Protein Subcellular Localization Based on Local Pairwise Profile Alignment and SVM
The subcellular locations of proteins are important functional annotations. An effective and reliable subcellular localization method is necessary for proteomics research. This pap...
Man-Wai Mak, Jian Guo, Sun-Yuan Kung
NCA
2006
IEEE
13 years 4 months ago
Analysing the localisation sites of proteins through neural networks ensembles
Scientists involved in the area of proteomics are currently seeking integrated, customised and validated research solutions to better expedite their work in proteomics analyses and...
Aristoklis D. Anastasiadis, George D. Magoulas
NC
2006
130views Neural Networks» more  NC 2006»
13 years 4 months ago
Dynamic self-assembly in living systems as computation
Biochemical reactions taking place in living systems that map different inputs to specific outputs are intuitively recognized as performing information processing. Conventional wis...
Ann M. Bouchard, Gordon C. Osbourn