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RECOMB
2005
Springer
10 years 10 months ago
Probabilistic in Silico Prediction of Protein-Peptide Interactions
Abstract. Peptide recognition modules (PRMs) are specialised compact protein domains that mediate many important protein-protein interactions. They are responsible for the assembly...
Wolfgang P. Lehrach, Dirk Husmeier, Christopher K....
RECOMB
2005
Springer
10 years 10 months ago
Examination of the tRNA Adaptation Index as a Predictor of Protein Expression Levels
Phenotypic differences between closely-related species may arise from differential expression regimes, rather than different gene complements. Knowledge of cellular protein levels ...
Orna Man, Joel L. Sussman, Yitzhak Pilpel
RECOMB
2005
Springer
10 years 10 months ago
An Interactive Map of Regulatory Networks of Pseudomonas aeruginosa Genome
For studying gene regulatory and protein signaling networks, we have developed an interactive map for the Pseudomonas aeruginosa genome. We first represent genes, proteins and the...
Weihui Wu, Yongling Song, Shouguang Jin, Su-Shing ...
RECOMB
2005
Springer
11 years 4 months ago
Decomposition of Overlapping Protein Complexes: A Graph Theoretical Method for Analyzing Static and Dynamic Protein Associations
Background: Most cellular processes are carried out by multi-protein complexes, groups of proteins that bind together to perform a specific task. Some proteins form stable complex...
Elena Zotenko, Katia S. Guimarães, Raja Jot...
RECOMB
2005
Springer
11 years 4 months ago
The Pathalyzer: A Tool for Analysis of Signal Transduction Pathways
Abstract. The Pathalyzer is a program for analyzing large-scale signal transduction networks. Reactions and their substrates and products are represented as transitions and places ...
David L. Dill, Merrill Knapp, Pamela Gage, Carolyn...
RECOMB
2005
Springer
11 years 4 months ago
Combinatorial Genetic Regulatory Network Analysis Tools for High Throughput Transcriptomic Data
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...
Elissa J. Chesler, Michael A. Langston
RECOMB
2005
Springer
11 years 4 months ago
Improved Duplication Models for Proteome Network Evolution
Protein-protein interaction networks, particularly that of the yeast S. Cerevisiae, have recently been studied extensively. These networks seem to satisfy the small world property ...
Gürkan Bebek, Petra Berenbrink, Colin Cooper,...
RECOMB
2005
Springer
11 years 4 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli
RECOMB
2005
Springer
11 years 4 months ago
Improved Pattern-Driven Algorithms for Motif Finding in DNA Sequences
Abstract. In order to guarantee that the optimal motif is found, traditional pattern-driven approaches perform an exhaustive search over all candidate motifs of length l. We develo...
Sing-Hoi Sze, Xiaoyan Zhao
RECOMB
2005
Springer
11 years 4 months ago
Comparative Systems Biology of the Sporulation Initiation Network in Prokaryotes
Many years of experimental and computational molecular biology of model organisms such as Escherichia coli and Saccharomyces cerevisiae has elucidated the gene regulatory network i...
Michiel J. L. de Hoon, Dennis Vitkup
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