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BMCBI
2008
142views more  BMCBI 2008»
13 years 4 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
BMCBI
2008
142views more  BMCBI 2008»
13 years 4 months ago
RNA STRAND: The RNA Secondary Structure and Statistical Analysis Database
Background: The ability to access, search and analyse secondary structures of a large set of known RNA molecules is very important for deriving improved RNA energy models, for eva...
Mirela Andronescu, Vera Bereg, Holger H. Hoos, Ann...
BMCBI
2008
116views more  BMCBI 2008»
13 years 4 months ago
A novel representation of RNA secondary structure based on element-contact graphs
Background: Depending on their specific structures, noncoding RNAs (ncRNAs) play important roles in many biological processes. Interest in developing new topological indices based...
Wenjie Shu, Xiaochen Bo, Zhiqiang Zheng, Shengqi W...
HPDC
2010
IEEE
13 years 5 months ago
Exploring the RNA folding energy landscape using scalable distributed cyberinfrastructure
The increasing significance of RNAs in transcriptional or post-transcriptional gene regulation processes has generated considerable interest towards the prediction of RNA folding ...
Joohyun Kim, Wei Huang, Sharath Maddineni, Fareed ...
CIBCB
2009
IEEE
13 years 5 months ago
rnaDesign: Local search for RNA secondary structure design
Abstract-- The RNA secondary structure design (SSD) problem is a recently emerging research topic motivated by applications such as customized drug design and the self-assembly of ...
Denny C. Dai, Herbert H. Tsang, Kay C. Wiese
BIOCOMP
2009
13 years 5 months ago
Consensus RNA Secondary Structure Prediction by Ranking k-Length Stems
The accurate computational prediction of RNA secondary structures is a difficult task, but an important one, since RNA structure is usually more evolutionarily conserved than prima...
Denise Y. F. Mak, Gary Benson
CSB
2004
IEEE
208views Bioinformatics» more  CSB 2004»
13 years 8 months ago
Pair Stochastic Tree Adjoining Grammars for Aligning and Predicting Pseudoknot RNA Structures
Motivation: Since the whole genome sequences for many species are currently available, computational predictions of RNA secondary structures and computational identifications of t...
Hiroshi Matsui, Kengo Sato, Yasubumi Sakakibara
WABI
2004
Springer
13 years 10 months ago
Novel Tree Edit Operations for RNA Secondary Structure Comparison
We describe an algorithm for comparing two RNA secondary structures coded in the form of trees that introduces two novel operations, called node fusion and edge fusion, besides the...
Julien Allali, Marie-France Sagot
SPIRE
2005
Springer
13 years 10 months ago
An Edit Distance Between RNA Stem-Loops
We introduce the notion of conservative edit distance and mapping between two RNA stem-loops. We show that unlike the general edit distance between RNA secondary structures, the co...
Valentin Guignon, Cedric Chauve, Sylvie Hamel
CSB
2005
IEEE
114views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Tree Decomposition Based Fast Search of RNA Structures Including Pseudoknots in Genomes
Searching genomes for RNA secondary structure with computational methods has become an important approach to the annotation of non-coding RNAs. However, due to the lack of effici...
Yinglei Song, Chunmei Liu, Russell L. Malmberg, Fa...