Current biological sequence comparison tools frequently fail to recognize matches between homologs when sequence similarity is below the twilight zone of less than 25% sequence id...
The minimal-length encoding approach is applied to define concept of sequence similarity. Asequence is defined to be similar to another sequence or to a set of keywords if it can ...
Biological sequence similarity analysis presents visualization challenges, primarily because of the massive amounts of discrete, multi-dimensional data. Genomic data generated by ...
Ed Huai-hsin Chi, Phillip Barry, Elizabeth Shoop, ...
Computational genomics involves comparing sequences based on “similarity” for detecting evolutionary and functional relationships. Until very recently, available portions of th...
Existing sequence comparison software applications lack automation, abstraction, performance, and flexibility. Users need a new way of studying and applying sequence comparisons i...
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...