eGIFT: Mining Gene Information from the Literature

Background: With the biomedical literature continually expanding, searching PubMed for information about specific genes becomes increasingly difficult. Not only can thousands of results be returned, but gene name ambiguity leads to many irrelevant hits. As a result, it is difficult for life scientists and gene curators to rapidly get an overall picture about a specific gene from documents that mention its names and synonyms. Results: In this paper, we present eGIFT (http://biotm.cis.udel.edu/eGIFT), a web-based tool that associates informative terms, called iTerms, and sentences containing them, with genes. To associate iTerms with a gene, eGIFT ranks iTerms about the gene, based on a score which compares the frequency of occurrence of a term in the gene's literature to its frequency of occurrence in documents about genes in general. To retrieve a gene's s (Medline abstracts), eGIFT considers all gene names, aliases, and synonyms. Since many of the gene names can be ambiguou...

• Type: Journal
• Year: 2010
• Where: BMCBI
• Authors: Catalina O. Tudor, Carl J. Schmidt, K. Vijay-Shanker
• Keywords: BMCBI 2010, Gene, Gene Names, Specific Gene