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2008

Multi-break rearrangements and chromosomal evolution

8 years 5 months ago
Multi-break rearrangements and chromosomal evolution
Most genome rearrangements (e.g., reversals and translocations) can be represented as 2-breaks that break a genome at 2 points and glue the resulting fragments in a new order. Multi-break rearrangements break a genome into multiple fragments and further glue them together in a new order. While multi-break rearrangements were studied in depth for k = 2 breaks, the k-break distance problem for arbitrary k remains unsolved. We prove a duality theorem for multi-break distance problem and give a polynomial algorithm for computing this distance. c 2008 Elsevier B.V. All rights reserved.
Max A. Alekseyev, Pavel A. Pevzner
Added 15 Dec 2010
Updated 15 Dec 2010
Type Journal
Year 2008
Where TCS
Authors Max A. Alekseyev, Pavel A. Pevzner
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