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» A Hidden Markov Model for de Novo Peptide Sequencing
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NIPS
2004
13 years 6 months ago
A Hidden Markov Model for de Novo Peptide Sequencing
De novo Sequencing of peptides is a challenging task in proteome research. While there exist reliable DNA-sequencing methods, the highthroughput de novo sequencing of proteins by ...
Bernd Fischer, Volker Roth, Joachim M. Buhmann, Jo...
DAGM
2006
Springer
13 years 8 months ago
Probabilistic De Novo Peptide Sequencing with Doubly Charged Ions
Sequencing of peptides by tandem mass spectrometry has matured to the key technology for proteomics. Noise in the measurement process strongly favors statistical models like NovoHM...
Hansruedi Peter, Bernd Fischer, Joachim M. Buhmann
NAR
2006
74views more  NAR 2006»
13 years 5 months ago
HHrep: de novo protein repeat detection and the origin of TIM barrels
HHrep is a web server for the de novo identification of repeats in protein sequences, which is based on the pairwise comparison of profile hidden Markov models (HMMs). Its main st...
Johannes Söding, Michael Remmert, Andreas Bie...
ISMB
1996
13 years 6 months ago
Parameterization Studies for the SAM and HMMER Methods of Hidden Markov Model Generation
Multiple sequence alignment of distantly related viral proteins remains a challenge to all currently available alignment methods. The hidden Markovmodel approach offers a new,flex...
Marcella A. McClure, Chris Smith, Pete Elton