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» A stepwise framework for the normalization of array CGH data
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BMCBI
2005
302views more  BMCBI 2005»
13 years 4 months ago
CGHPRO - A comprehensive data analysis tool for array CGH
Background: Array CGH (Comparative Genomic Hybridisation) is a molecular cytogenetic technique for the genome wide detection of chromosomal imbalances. It is based on the cohybrid...
Wei Chen, Fikret Erdogan, H.-Hilger Ropers, Steffe...
ISBRA
2009
Springer
13 years 11 months ago
A Linear-Time Algorithm for Analyzing Array CGH Data Using Log Ratio Triangulation
Abstract. DNA copy number is the number of replicates of a contiguous segment of DNA on the genome. Copy number alteration (CNA) is a genetic abnormality in which the number of the...
Matthew Hayes, Jing Li
BMCBI
2007
180views more  BMCBI 2007»
13 years 4 months ago
Using expression arrays for copy number detection: an example from E. coli
Background: The sequencing of many genomes and tiling arrays consisting of millions of DNA segments spanning entire genomes have made high-resolution copy number analysis possible...
Dmitriy Skvortsov, Diana Abdueva, Michael E. Stitz...
BMCBI
2010
161views more  BMCBI 2010»
13 years 5 months ago
CGHpower: exploring sample size calculations for chromosomal copy number experiments
Background: Determining a suitable sample size is an important step in the planning of microarray experiments. Increasing the number of arrays gives more statistical power, but ad...
Ilari Scheinin, Jose A. Ferreira, Sakari Knuutila,...
RECOMB
2007
Springer
14 years 5 months ago
Framework for Identifying Common Aberrations in DNA Copy Number Data
High-resolution array comparative genomic hybridization (aCGH) provides exon-level mapping of DNA aberrations in cells or tissues. Such aberrations are central to carcinogenesis an...
Amir Ben-Dor, Doron Lipson, Anya Tsalenko, Mark Re...