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» Accurate detection of very sparse sequence motifs
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RECOMB
2003
Springer
14 years 5 months ago
Accurate detection of very sparse sequence motifs
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
Andreas Heger, Michael Lappe, Liisa Holm
BMCBI
2006
144views more  BMCBI 2006»
13 years 5 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...
GECCO
2006
Springer
159views Optimization» more  GECCO 2006»
13 years 8 months ago
Identification of weak motifs in multiple biological sequences using genetic algorithm
Recognition of motifs in multiple unaligned sequences provides an insight into protein structure and function. The task of discovering these motifs is very challenging because mos...
Topon Kumar Paul, Hitoshi Iba
BMCBI
2007
125views more  BMCBI 2007»
13 years 5 months ago
Statistical tests to compare motif count exceptionalities
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...
Stéphane Robin, Sophie Schbath, Vincent Van...
BIRD
2008
Springer
162views Bioinformatics» more  BIRD 2008»
13 years 7 months ago
Suffix Tree Characterization of Maximal Motifs in Biological Sequences
Finding motifs in biological sequences is one of the most intriguing problems for string algorithms designers due to, on the one hand, the numerous applications of this problem in...
Maria Federico, Nadia Pisanti