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ISMB
1994
13 years 6 months ago
An Improved System for Exon Recognition and Gene Modeling in Human DNA Sequence
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
ALMOB
2006
155views more  ALMOB 2006»
13 years 5 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2006
111views more  BMCBI 2006»
13 years 5 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
ISMB
1996
13 years 6 months ago
Finding Genes in DNA Using Decision Trees and Dynamic Programming
This study demonstratesthe use of decision tree classifiers as the basis for a general gene-finding system. The system uses a dynamic programmingalgorithm that. finds the optimal ...
Steven Salzberg, Xin Chen, John Henderson, Kenneth...
CSB
2002
IEEE
121views Bioinformatics» more  CSB 2002»
13 years 10 months ago
Fast and Sensitive Algorithm for Aligning ESTs to Human Genome
There is a pressing need to align growing set of expressed sequence tags (ESTs) to newly sequenced human genome. The problem is, however, complicated by the exon/intron structure ...
Jun Ogasawara, Shinichi Morishita