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» Comparing Sequences with Segment Rearrangements
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JCB
2008
111views more  JCB 2008»
13 years 5 months ago
Sorting Genomes with Centromeres by Translocations
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromer...
Michal Ozery-Flato, Ron Shamir
JCB
2007
78views more  JCB 2007»
13 years 5 months ago
Sorting by Reciprocal Translocations via Reversals Theory
The understanding of genome rearrangements is an important endeavor in comparative genomics. A major computational problem in this field is finding a shortest sequence of genome...
Michal Ozery-Flato, Ron Shamir
RECOMB
2004
Springer
14 years 6 months ago
Estimators of Translocations and Inversions in Comparative Maps
In a comparative map, the number of translocations in the evolutionary history of a chromosome can be estimated solely on the basis of the conserved syntenies it contains. This est...
David Sankoff, Matthew Mazowita
BMCBI
2010
100views more  BMCBI 2010»
13 years 5 months ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...
BMCBI
2007
89views more  BMCBI 2007»
13 years 5 months ago
Comparing segmentations by applying randomization techniques
Background: There exist many segmentation techniques for genomic sequences, and the segmentations can also be based on many different biological features. We show how to evaluate ...
Niina Haiminen, Heikki Mannila, Evimaria Terzi