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BMCBI
2008
153views more  BMCBI 2008»
13 years 5 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani
GCB
2004
Springer
101views Biometrics» more  GCB 2004»
13 years 10 months ago
Kleene's Theorem and the Solution of Metabolic Carbon Labeling Systems
: Carbon Labeling Systems (CLS) are large equation systems that describe the dynamics of labeled carbon atoms in a metabolic network. The rapid solution of these systems is the alg...
Nicole Isermann, Michael Weitzel, Wolfgang Wiecher...
WABI
2005
Springer
124views Bioinformatics» more  WABI 2005»
13 years 10 months ago
Reconstructing Metabolic Networks Using Interval Analysis
Recently, there has been growing interest in the modelling and simulation of biological systems. Such systems are often modelled in terms of coupled ordinary differential equation...
Warwick Tucker, Vincent Moulton
BMCBI
2007
101views more  BMCBI 2007»
13 years 5 months ago
Robust detection and verification of linear relationships to generate metabolic networks using estimates of technical errors
Background: The size and magnitude of the metabolome, the ratio between individual metabolites and the response of metabolic networks is controlled by multiple cellular factors. A...
Frank Kose, Jan Budczies, Matthias Holschneider, O...
BMCBI
2006
107views more  BMCBI 2006»
13 years 5 months ago
Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum
Background: Quantification of the metabolic network of an organism offers insights into possible ways of developing mutant strain for better productivity of an extracellular metab...
Kalyan Gayen, K. V. Venkatesh