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BIBM
2008
IEEE
137views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Exploring Alternative Splicing Features Using Support Vector Machines
Alternative splicing is a mechanism for generating different gene transcripts (called isoforms) from the same genomic sequence. Finding alternative splicing events experimentally ...
Jing Xia, Doina Caragea, Susan Brown
BMCBI
2008
162views more  BMCBI 2008»
13 years 4 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
BMCBI
2008
93views more  BMCBI 2008»
13 years 4 months ago
Hybrid MM/SVM structural sensors for stochastic sequential data
In this paper we present preliminary results stemming from a novel application of Markov Models and Support Vector Machines to splice site classification of Intron-Exon and Exon-I...
Brian Roux, Stephen Winters-Hilt
BMCBI
2008
102views more  BMCBI 2008»
13 years 4 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...
BMCBI
2006
82views more  BMCBI 2006»
13 years 4 months ago
Profiling alternatively spliced mRNA isoforms for prostate cancer classification
Background: Prostate cancer is one of the leading causes of cancer illness and death among men in the United States and world wide. There is an urgent need to discover good biomar...
Chaolin Zhang, Hai-Ri Li, Jian-Bing Fan, Jessica W...