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BMCBI
2007
233views more  BMCBI 2007»
13 years 5 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
ISPDC
2007
IEEE
13 years 11 months ago
Whole Genome Comparison on a Network of Workstations
Whole genome comparison consists of comparing or aligning genome sequences with a goal of finding similarities between them. Previously we have shown how SIMD Extensions used in ...
Arpith C. Jacob, Sugata Sanyal, Marcin Paprzycki, ...
BIBE
2008
IEEE
142views Bioinformatics» more  BIBE 2008»
13 years 11 months ago
Optimizing performance, cost, and sensitivity in pairwise sequence search on a cluster of PlayStations
— The Smith-Waterman algorithm is a dynamic programming method for determining optimal local alignments between nucleotide or protein sequences. However, it suffers from quadrati...
Ashwin M. Aji, Wu-chun Feng
PROCEDIA
2010
138views more  PROCEDIA 2010»
12 years 11 months ago
Using the reconfigurable massively parallel architecture COPACOBANA 5000 for applications in bioinformatics
Currently several computational problems require high processing power to handle huge amounts of data, although underlying core algorithms appear to be rather simple. Especially i...
Lars Wienbrandt, Stefan Baumgart, Jost Bissel, Car...
IPPS
2006
IEEE
13 years 11 months ago
Bio-sequence database scanning on a GPU
Protein sequences with unknown functionality are often compared to a set of known sequences to detect functional similarities. Efficient dynamic programming algorithms exist for t...
Weiguo Liu, Bertil Schmidt, Gerrit Voss, Adrian Sc...