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» Feature Engineering for a Gene Regulation Prediction Task
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ISBRA
2009
Springer
14 years 15 days ago
Integrating Multiple-Platform Expression Data through Gene Set Features
Abstract. We demonstrate a set-level approach to the integration of multiple platform gene expression data for predictive classification and show its utility for boosting classi...
Matej Holec, Filip Zelezný, Jirí Kl&...
BMCBI
2007
106views more  BMCBI 2007»
13 years 5 months ago
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
NAR
2007
132views more  NAR 2007»
13 years 5 months ago
TRED: a transcriptional regulatory element database, new entries and other development
Transcriptional factors (TFs) and many of their target genes are involved in gene regulation at the level of transcription. To decipher gene regulatory networks (GRNs) we require ...
C. Jiang, Zhenyu Xuan, Fang Zhao, Michael Q. Zhang
CISIS
2010
IEEE
13 years 3 months ago
Modeling of Stress-induced Regulatory Cascades Involving Transcription Factor Dimers
Regulatory cascades consisting of stress-induced gene modules and their transcriptional regulators were recently identified and quantitatively modeled using Artificial Neural Netwo...
Maria Manioudaki, Panayiota Poirazi
BMCBI
2008
82views more  BMCBI 2008»
13 years 5 months ago
Studying the functional conservation of cis-regulatory modules and their transcriptional output
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
Denis C. Bauer, Timothy L. Bailey