Abstract. We demonstrate a set-level approach to the integration of multiple platform gene expression data for predictive classification and show its utility for boosting classi...
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
Transcriptional factors (TFs) and many of their target genes are involved in gene regulation at the level of transcription. To decipher gene regulatory networks (GRNs) we require ...
C. Jiang, Zhenyu Xuan, Fang Zhao, Michael Q. Zhang
Regulatory cascades consisting of stress-induced gene modules and their transcriptional regulators were recently identified and quantitatively modeled using Artificial Neural Netwo...
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...