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» Finding Dynamic Modules of Biological Regulatory Networks
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BIBE
2010
IEEE
135views Bioinformatics» more  BIBE 2010»
13 years 5 months ago
Finding Dynamic Modules of Biological Regulatory Networks
—Often groups of genes in regulatory networks, also called modules, work collaboratively on similar functions. Mathematically, the modules in a regulatory network has often been ...
Ferhat Ay, Thang N. Dinh, My T. Thai, Tamer Kahvec...
BMCBI
2010
153views more  BMCBI 2010»
13 years 3 months ago
DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
Bruno M. Tesson, Rainer Breitling, Ritsert C. Jans...
BMCBI
2007
186views more  BMCBI 2007»
13 years 5 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
BMCBI
2011
12 years 12 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
CIBCB
2005
IEEE
13 years 10 months ago
Network Motifs, Feedback Loops and the Dynamics of Genetic Regulatory Networks
We analyse a suite of Boolean networks which have been evolved to exhibit limit cycle-type dynamics in terms of the distribution of small network motifs and feedback loops. We find...
Jennifer Hallinan, Paul T. Jackway