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CIBCB
2005
IEEE
13 years 10 months ago
Functional Distances for Genes Based on GO Feature Maps and their Application to Clustering
— With the invention of high throughput methods, researchers are capable of producing large amounts of biological data. During the analysis of such data, the need for a functiona...
Nora Speer, Holger Fröhlich, Christian Spieth...
CBMS
2008
IEEE
13 years 11 months ago
A New Path Length Measure Based on GO for Gene Similarity with Evaluation using SGD Pathways
We propose a new method for measuring the semantic similarity of genes based on path length between their annotation terms in the Gene Ontology. Our method applies an exponential ...
Anurag Nagar, Hisham Al-Mubaid
CSB
2004
IEEE
173views Bioinformatics» more  CSB 2004»
13 years 8 months ago
Gene Ontology Friendly Biclustering of Expression Profiles
The soundness of clustering in the analysis of gene expression profiles and gene function prediction is based on the hypothesis that genes with similar expression profiles may imp...
Jinze Liu, Wei Wang 0010, Jiong Yang
BMCBI
2008
200views more  BMCBI 2008»
13 years 5 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BIBM
2008
IEEE
212views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Analysis of Multiplex Gene Expression Maps Obtained by Voxelation
Background: Gene expression signatures in the mammalian brain hold the key to understanding neural development and neurological disease. Researchers have previously used voxelatio...
Li An, Hongbo Xie, Mark H. Chin, Zoran Obradovic, ...