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RECOMB
2003
Springer
14 years 4 months ago
Accurate detection of very sparse sequence motifs
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
Andreas Heger, Michael Lappe, Liisa Holm
BMCBI
2006
116views more  BMCBI 2006»
13 years 4 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2007
131views more  BMCBI 2007»
13 years 4 months ago
FUNC: a package for detecting significant associations between gene sets and ontological annotations
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
Kay Prüfer, Bjoern Muetzel, Hong Hai Do, Gunt...