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GECCO
2006
Springer
159views Optimization» more  GECCO 2006»
13 years 8 months ago
Identification of weak motifs in multiple biological sequences using genetic algorithm
Recognition of motifs in multiple unaligned sequences provides an insight into protein structure and function. The task of discovering these motifs is very challenging because mos...
Topon Kumar Paul, Hitoshi Iba
GECCO
2007
Springer
258views Optimization» more  GECCO 2007»
13 years 9 months ago
TFBS identification by position- and consensus-led genetic algorithm with local filtering
Identification of Transcription Factor Binding Site (TFBS) motifs in multiple DNA upstream sequences is important in understanding the mechanism of gene regulation. This identific...
Tak-Ming Chan, Kwong-Sak Leung, Kin-Hong Lee
RECOMB
2003
Springer
14 years 5 months ago
Whole-genome comparative annotation and regulatory motif discovery in multiple yeast species
In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae. Genome-wide comp...
Manolis Kamvysselis, Nick Patterson, Bruce Birren,...
WABI
2007
Springer
13 years 11 months ago
A Graph Clustering Approach to Weak Motif Recognition
The aim of the motif recognition problem is to detect a set of mutually similar subsequences within a collection of biological sequences. The weak motif recognition problem on DNA ...
Christina Boucher, Daniel G. Brown, Paul Church
RECOMB
2001
Springer
14 years 5 months ago
Finding motifs using random projections
motif discovery problem abstracts the task of discovering short, conserved sites in genomic DNA. Pevzner and Sze recently described a precise combinatorial formulation of motif di...
Jeremy Buhler, Martin Tompa