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NIPS
2004
13 years 6 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
ENGL
2008
121views more  ENGL 2008»
13 years 4 months ago
Prediction of Protein-Protein Interactions Using Pairwise Alignment and Inter-Domain Linker Region
One of the central problems in modern biology is to identify the complete set of interactions among the proteins in a cell. The structural interaction of proteins and their domains...
Nazar Zaki
CSB
2002
IEEE
230views Bioinformatics» more  CSB 2002»
13 years 9 months ago
Prediction of Protein Function Using Protein-Protein Interaction Data
Assigning functions to novel proteins is one of the most important problems in the post-genomic era. Several approaches have been applied to this problem, including analyzing gene...
Minghua Deng, Kui Zhang, Shipra Mehta, Ting Chen, ...
RECOMB
2006
Springer
14 years 5 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
CSB
2005
IEEE
141views Bioinformatics» more  CSB 2005»
13 years 10 months ago
A Parallel Algorithm for Clustering Protein-Protein Interaction Networks
The increasing availability of interaction graphs requires new resource-efficient tools capable of extracting valuable biological knowledge from these networks. In this paper we ...
Qiaofeng Yang, Stefano Lonardi