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» Pairwise Alignment of Protein Interaction Networks
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BIBM
2008
IEEE
141views Bioinformatics» more  BIBM 2008»
13 years 12 months ago
Protein-Protein Interaction Network Alignment by Quantitative Simulation
We adapt a network simulation algorithm called quantitative simulation (QSim) for use in the alignment of biological networks. Unlike most network alignment methods, QSim finds l...
Perry Evans, Ted Sandler, Lyle H. Ungar
LION
2009
Springer
135views Optimization» more  LION 2009»
13 years 12 months ago
Neural Network Pairwise Interaction Fields for Protein Model Quality Assessment
We present a new knowledge-based Model Quality Assessment Program (MQAP) at the residue level which evaluates single protein structure models. We use a tree representation of the ...
Alberto J. M. Martin, Alessandro Vullo, Gianluca P...
AINA
2008
IEEE
13 years 12 months ago
Protein Structure Comparison and Alignment Using Residue Contexts
We introduce a method for comparing protein structures using the notion of residue contexts based on protein Cα-atom backbones. The residue context is derived from the set of vec...
Tobias Sayre, Rahul Singh
BMCBI
2005
198views more  BMCBI 2005»
13 years 5 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
BIBM
2009
IEEE
151views Bioinformatics» more  BIBM 2009»
14 years 6 days ago
Detection of Gene Orthology Based on Protein-Protein Interaction Networks
Abstract—Ortholog detection methods present a powerful approach for finding genes that participate in similar biological processes across different organisms, extending our unde...
Fadi Towfic, M. Heather West Greenlee, Vasant Hona...