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» Predicting Enzyme Function from Sequence: A Systematic Appra...
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ISMB
1997
13 years 6 months ago
Prediction of Enzyme Classification from Protein Sequence without the Use of Sequence Similarity
1 W’edescribe a novel approach for predicting the function of a protein from its amino-acid sequence. Given features that can be computedfrom the amino-acid sequence in a straigh...
Marie desJardins, Peter D. Karp, Markus Krummenack...
BMCBI
2007
127views more  BMCBI 2007»
13 years 4 months ago
CORRIE: enzyme sequence annotation with confidence estimates
Using a previously developed automated method for enzyme annotation, we report the reannotation of the ENZYME database and the analysis of local error rates per class. In control ...
Benjamin Audit, Emmanuel D. Levy, Walter R. Gilks,...
BMCBI
2010
155views more  BMCBI 2010»
13 years 2 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
BMCBI
2010
141views more  BMCBI 2010»
13 years 5 months ago
Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles
Background: Enzymes belonging to acyl:CoA synthetase (ACS) superfamily activate wide variety of substrates and play major role in increasing the structural and functional diversit...
Pankaj Khurana, Rajesh S. Gokhale, Debasisa Mohant...