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NAR
2010
107views more  NAR 2010»
13 years 6 days ago
FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database
FlyTF (http://www.flytf.org) is a database of computationally predicted and/or experimentally verified site-specific transcription factors (TFs) in the fruit fly Drosophila melano...
Ulrike Pfreundt, Daniel P. James, Susan Tweedie, D...
BMCBI
2011
13 years 13 days ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein
RECOMB
2008
Springer
14 years 5 months ago
BayCis: A Bayesian Hierarchical HMM for Cis-Regulatory Module Decoding in Metazoan Genomes
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
Tien-ho Lin, Pradipta Ray, Geir Kjetil Sandve, Sel...
BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
13 years 9 months ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu
FUZZIEEE
2007
IEEE
13 years 11 months ago
Mining and Predicting CpG islands
— A DNA sequence can be described as a string composed of four symbols: A, T, C and G. Each symbol represents a chemically distinct nucleotide molecule. Combinations of two nucle...
Christopher Previti, Oscar Harari, Coral del Val