Understanding the protein folding mechanism remains a grand challenge in structural biology. In the past several years, computational theories in molecular dynamics have been empl...
Background: The process of oxidative folding combines the formation of native disulfide bond with conformational folding resulting in the native three-dimensional fold. Oxidative ...
The paper describes a constraint-based solution to the protein folding problem on face-centered cubic lattices—a biologically meaningful approximation of the general protein fol...
Abstract. The topology of β-sheets is defined by the pattern of hydrogenbonded strand pairing. Therefore, predicting hydrogen bonded strand partners is a fundamental step towards...
Protein fold recognition is the prediction of protein’s tertiary structure (Fold) given the protein’s sequence without relying on sequence similarity. Using machine learning t...