19 search results - page 2 / 4 » Primer design for multiplex PCR using a genetic algorithm |
BMCBI
2010
13 years 5 months ago
2010
Background: Polymerase chain reaction with confronting two-pair primers (PCR-CTPP) method produces allelespecific DNA bands of different lengths by adding four designed primers an...
BMCBI
2005
13 years 5 months ago
2005
Background: A new algorithm for assessing similarity between primer and template has been developed based on the hypothesis that annealing of primer to template is an information ...
ISMB
1997
13 years 7 months ago
1997
Weinvestigate the problemof designingefficient multiplex PCRfor medical applications. Weshowthat the problemis NP-completeby transformation to the Multiple Choice Matchingproblema...
BMCBI
2008
13 years 5 months ago
2008
Background: Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utili...
BMCBI
2006
13 years 5 months ago
2006
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...