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» Probabilistic Model Checking of Complex Biological Pathways
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BIBE
2009
IEEE
252views Bioinformatics» more  BIBE 2009»
14 years 1 days ago
Multi-Agents System to Model Cell Signalling by Using Fuzzy Cognitive Maps. Application to Computer Simulation of Multiple Myelo
—In order to simulate biological processes, we use multi-agents system. However, modelling cell behavior in systems biology is complex and may be based on intracellular biochemic...
Vincent Rodin, Gabriel Querrec, Pascal Ballet, Fra...
BMCBI
2010
143views more  BMCBI 2010»
13 years 5 months ago
An efficient biological pathway layout algorithm combining grid-layout and spring embedder for complicated cellular location inf
Background: Graph drawing is one of the important techniques for understanding biological regulations in a cell or among cells at the pathway level. Among many available layout al...
Kaname Kojima, Masao Nagasaki, Satoru Miyano
BIB
2008
93views more  BIB 2008»
13 years 5 months ago
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology. Buildin...
Rainer Breitling, David Gilbert, Monika Heiner, Ri...
RECOMB
2004
Springer
14 years 5 months ago
Discovering temporal relations in molecular pathways using protein-protein interactions
The availability of large-scale protein-protein interaction data provides us with many opportunities to study molecular pathways involving proteins. In this paper we propose to mi...
Martin Farach-Colton, Yang Huang, John L. L. Woolf...
BMCBI
2006
145views more  BMCBI 2006»
13 years 5 months ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...