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CSB
2003
IEEE
106views Bioinformatics» more  CSB 2003»
13 years 9 months ago
Reconstruction of Ancestral Gene Order after Segmental Duplication and Gene Loss
As gene order evolves through a variety of chromosomal rearrangements, conserved segments provide important insight into evolutionary relationships and functional roles of genes. ...
Jun Huan, Jan Prins, Wei Wang 0010, Todd J. Vision
RECOMB
2012
Springer
11 years 7 months ago
A Model for Biased Fractionation after Whole Genome Duplication
Background: Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion...
David Sankoff, Chunfang Zheng, Baoyong Wang
JCB
2008
102views more  JCB 2008»
13 years 4 months ago
DUPCAR: Reconstructing Contiguous Ancestral Regions with Duplications
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorit...
Jian Ma, Aakrosh Ratan, Brian J. Raney, Bernard B....
RECOMB
2007
Springer
14 years 4 months ago
A Heuristic Algorithm for Reconstructing Ancestral Gene Orders with Duplications
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorith...
Jian Ma, Aakrosh Ratan, Louxin Zhang, Webb Miller,...
WABI
2004
Springer
100views Bioinformatics» more  WABI 2004»
13 years 10 months ago
Reversing Gene Erosion - Reconstructing Ancestral Bacterial Genomes from Gene-Content and Order Data
In the last few years, it has become routine to use gene-order data to reconstruct phylogenies, both in terms of edge distances (parsimonious sequences of operations that transform...
Joel V. Earnest-DeYoung, Emmanuelle Lerat, Bernard...