Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Genetic Algorithms (GAs), as nondeterministic conformational search techniques, are promising for solving protein structure prediction (PSP) problems. The crossover operator of a ...
Tamjidul Hoque, Madhu Chetty, Andrew Lewis, Abdul ...
The prediction of protein 3D structure has become a hot research area in the post-genome era, through which people can understand a protein’s function in health and disease, exp...
Wenlong Li, Tao Wang, Eric Li, D. Baker, Li Jin, S...
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...