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» Using motion planning to study protein folding pathways
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RECOMB
2006
Springer
14 years 5 months ago
Simulating Protein Motions with Rigidity Analysis
Abstract. Protein motions, ranging from molecular flexibility to largescale conformational change, play an essential role in many biochemical processes. Despite the explosion in ou...
Shawna L. Thomas, Xinyu Tang, Lydia Tapia, Nancy M...
RECOMB
2004
Springer
14 years 5 months ago
Using motion planning to study RNA folding kinetics
We propose a novel, motion planning based approach to approximately map the energy landscape of an RNA molecule. Our method is based on the successful probabilistic roadmap motion...
Xinyu Tang, Bonnie Kirkpatrick, Shawna L. Thomas, ...
BMCBI
2008
168views more  BMCBI 2008»
13 years 5 months ago
Predicting protein folding pathways at the mesoscopic level based on native interactions between secondary structure elements
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...
Qingwu Yang, Sing-Hoi Sze
ALMOB
2007
170views more  ALMOB 2007»
13 years 5 months ago
A spatio-temporal mining approach towards summarizing and analyzing protein folding trajectories
Understanding the protein folding mechanism remains a grand challenge in structural biology. In the past several years, computational theories in molecular dynamics have been empl...
Hui Yang, Srinivasan Parthasarathy, Duygu Ucar