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BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
9 years 8 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
9 years 10 months ago
On the Role of Local Matching for Efficient Semi-supervised Protein Sequence Classification
Recent studies in protein sequence analysis have leveraged the power of unlabeled data. For example, the profile and mismatch neighborhood kernels have shown significant improveme...
Pavel P. Kuksa, Pai-Hsi Huang, Vladimir Pavlovic
BIBM
2008
IEEE
106views Bioinformatics» more  BIBM 2008»
9 years 10 months ago
Invariance Kernel of Biological Regulatory Networks
: The analysis of Biological Regulatory Network (BRN) leads to compute the set of the possible behaviours of the biological components. These behaviours are seen as trajectories an...
Jamil Ahmad, Olivier Roux
BIBM
2008
IEEE
106views Bioinformatics» more  BIBM 2008»
9 years 10 months ago
Uncovering Genomic Reassortments among Influenza Strains by Enumerating Maximal Bicliques
The evolutionary histories of viral genomes have received significant recent attention due to their importance in understanding virulence and the corresponding ramifications to pu...
Niranjan Nagarajan, Carl Kingsford
BIBM
2008
IEEE
110views Bioinformatics» more  BIBM 2008»
10 years 2 months ago
Genome Alignments Using MPI-LAGAN
We develop a parallel algorithm for a widely used whole genome alignment method called LAGAN. We use the MPI-based protocol to develop parallel solutions for two phases of the alg...
Ruinan Zhang, Huzefa Rangwala, George Karypis
BIBM
2008
IEEE
107views Bioinformatics» more  BIBM 2008»
10 years 2 months ago
Multiway Clustering for Creating Biomedical Term Sets
We present an EM-based clustering method that can be used for constructing or augmenting ontologies such as MeSH. Our algorithm simultaneously clusters verbs and nouns using both ...
Vasileios Kandylas, Lyle H. Ungar, Ted Sandler, Sh...
BIBM
2008
IEEE
113views Bioinformatics» more  BIBM 2008»
10 years 2 months ago
Towards Site-Based Protein Functional Annotations
Abstract—The exact relationship between protein active centers and protein functions is unclear even after decades of intensive study. To improve the functional prediction abilit...
Seak Fei Lei, Jun Huan
BIBM
2008
IEEE
172views Bioinformatics» more  BIBM 2008»
10 years 2 months ago
Boosting Methods for Protein Fold Recognition: An Empirical Comparison
Protein fold recognition is the prediction of protein’s tertiary structure (Fold) given the protein’s sequence without relying on sequence similarity. Using machine learning t...
Yazhene Krishnaraj, Chandan K. Reddy
BIBM
2008
IEEE
141views Bioinformatics» more  BIBM 2008»
10 years 2 months ago
Protein-Protein Interaction Network Alignment by Quantitative Simulation
We adapt a network simulation algorithm called quantitative simulation (QSim) for use in the alignment of biological networks. Unlike most network alignment methods, QSim finds l...
Perry Evans, Ted Sandler, Lyle H. Ungar
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