BMCBI
2006
13 years 4 months ago
2006
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
BMCBI
2006
13 years 4 months ago
2006
Background: The Gene Ontology has become an extremely useful tool for the analysis of genomic data and structuring of biological knowledge. Several excellent software tools for na...
BMCBI
2006
13 years 4 months ago
2006
Background: Comparison of large protein datasets has become a standard task in bioinformatics. Typically researchers wish to know whether one group of proteins is significantly en...
BMCBI
2006
13 years 4 months ago
2006
Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
BMCBI
2006
13 years 4 months ago
2006
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
BMCBI
2006
13 years 4 months ago
2006
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
BMCBI
2006
13 years 4 months ago
2006
Background: The rapidly increasing speed with which genome sequence data can be generated will be accompanied by an exponential increase in the number of sequenced eukaryotes. Wit...
BMCBI
2006
13 years 4 months ago
2006
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
BMCBI
2006
13 years 4 months ago
2006
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...