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BMCBI
2008
128views more  BMCBI 2008»
9 years 3 months ago
In silico analysis of expressed sequence tags from Trichostrongylus vitrinus (Nematoda): comparison of the automated ESTExplorer
Background: The analysis of expressed sequence tags (EST) offers a rapid and cost effective approach to elucidate the transcriptome of an organism, but requires several computatio...
Shivashankar H. Nagaraj, Robin B. Gasser, Alasdair...
BMCBI
2008
184views more  BMCBI 2008»
9 years 3 months ago
"TOF2H": A precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI
Background: Protein-amide proton hydrogen-deuterium exchange (HDX) is used to investigate protein conformation, conformational changes and surface binding sites for other molecule...
Pornpat Nikamanon, Elroy Pun, Wayne Chou, Marek D....
BMCBI
2007
80views more  BMCBI 2007»
9 years 3 months ago
Mining expression-dependent modules in the human interaction network
ent> <title> <p>Highlights from the Third International Society for Computational Biology (ISCB) Student Council Symposium at the Fifteenth Annual International Conf...
Elisabeth Georgii, Sabine Dietmann, Takeaki Uno, P...
BMCBI
2007
169views more  BMCBI 2007»
9 years 3 months ago
Transcription factor target prediction using multiple short expression time series from Arabidopsis thaliana
Background: The central role of transcription factors (TFs) in higher eukaryotes has led to much interest in deciphering transcriptional regulatory interactions. Even in the best ...
Henning Redestig, Daniel Weicht, Joachim Selbig, M...
BMCBI
2007
59views more  BMCBI 2007»
9 years 3 months ago
Environment specific substitution tables for thermophilic proteins
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...
K. Mizuguchi, M. Sele, Maria Vittoria Cubellis
BMCBI
2007
92views more  BMCBI 2007»
9 years 3 months ago
Nanopore current transduction analysis of protein binding to non-terminal and terminal DNA regions: analysis of transcription fa
Background: Synthetic transcription factors (STFs) promise to offer a powerful new therapeutic against Cancer, AIDS, and genetic disease. Currently, 10% of drugs are of this type,...
Stephen Winters-Hilt, Amanda Davis, Iftekhar Amin,...
BMCBI
2007
104views more  BMCBI 2007»
9 years 3 months ago
Validating module network learning algorithms using simulated data
Tom Michoel, Steven Maere, Eric Bonnet, Anagha Jos...
BMCBI
2007
155views more  BMCBI 2007»
9 years 3 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
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