BMCBI
2007
13 years 5 months ago
2007
Background: Although prognostic biomarkers specific for particular cancers have been discovered, microarray analysis of gene expression profiles, supported by integrative analysis...
BMCBI
2007
13 years 5 months ago
2007
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
BMCBI
2007
13 years 5 months ago
2007
Background: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the co...
BMCBI
2007
13 years 5 months ago
2007
Background: Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. Howeve...
BMCBI
2007
13 years 5 months ago
2007
Background: To interpret microarray experiments, several ontological analysis tools have been developed. However, current tools are limited to specific organisms. Results: We deve...
BMCBI
2007
13 years 5 months ago
2007
Background: The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequenc...
BMCBI
2007
13 years 5 months ago
2007
Background: A nearly complete collection of gene-deletion mutants (96% of annotated open reading frames) of the yeast Saccharomyces cerevisiae has been systematically constructed....
BMCBI
2007
13 years 5 months ago
2007
Background: Recent research examining cross-platform correlation of gene expression intensities has yielded mixed results. In this study, we demonstrate use of a correction factor...
BMCBI
2007
13 years 5 months ago
2007
Background: Knowing the subcellular location of proteins provides clues to their function as well as the interconnectivity of biological processes. Dozens of tools are available f...
BMCBI
2007
13 years 5 months ago
2007
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...