BMCBI
2007
13 years 5 months ago
2007
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
BMCBI
2007
13 years 5 months ago
2007
Background: With the popularisation of high-throughput techniques, the need for procedures that help in the biological interpretation of results has increased enormously. Recently...
BMCBI
2007
13 years 5 months ago
2007
Background: Natural antisense transcripts (NATs) are endogenous RNA molecules that exhibit partial or complete complementarity to other RNAs, and that may contribute to the regula...
BMCBI
2007
13 years 5 months ago
2007
Background: This paper presents a unified framework for finding differentially expressed genes (DEGs) from the microarray data. The proposed framework has three interrelated modul...
BMCBI
2007
13 years 5 months ago
2007
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
BMCBI
2007
13 years 5 months ago
2007
Background: Identification of the structural domains of proteins is important for our understanding of the organizational principles and mechanisms of protein folding, and for ins...
BMCBI
2007
13 years 5 months ago
2007
Background: Microarray compendia profile the expression of genes in a number of experimental conditions. Such data compendia are useful not only to group genes and conditions base...
BMCBI
2007
13 years 5 months ago
2007
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
BMCBI
2007
13 years 5 months ago
2007
Background: Numerous functional genomics approaches have been developed to study the model organism yeast, Saccharomyces cerevisiae, with the aim of systematically understanding t...