BMCBI
2007
13 years 5 months ago
2007
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
BMCBI
2007
13 years 5 months ago
2007
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
BMCBI
2007
2007
FUNC: a package for detecting significant associations between gene sets and ontological annotations
13 years 5 months ago
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
BMCBI
2007
13 years 5 months ago
2007
Background: As a consequence of the evolutionary process, data collected from related species tend to be similar. This similarity by descent can obscure subtler signals in the dat...
BMCBI
2007
13 years 5 months ago
2007
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
BMCBI
2007
13 years 5 months ago
2007
Background: With the explosion in data generated using microarray technology by different investigators working on similar experiments, it is of interest to combine results across...
BMCBI
2007
13 years 5 months ago
2007
Background: In recent years, RNA molecules that are not translated into proteins (ncRNAs) have drawn a great deal of attention, as they were shown to be involved in many cellular ...
BMCBI
2007
13 years 5 months ago
2007
Background: Solenoid repeat proteins of the Tetratrico Peptide Repeat (TPR) family are involved as scaffolds in a broad range of protein-protein interactions. Several resources ar...
BMCBI
2007
13 years 5 months ago
2007
Background: The ability to visualize genomic features and design experimental assays that can target specific regions of a genome is essential for modern biology. To assist in the...
BMCBI
2007
13 years 5 months ago
2007
Background: Many algorithms exist for protein structural alignment, based on internal protein coordinates or on explicit superposition of the structures. These methods are usually...