BMCBI
2011
12 years 11 months ago
2011
Background: As one of the most widely used parsimony methods for ancestral reconstruction, the Fitch method minimizes the total number of hypothetical substitutions along all bran...
BMCBI
2011
12 years 11 months ago
2011
Background: The Cancer Genome Anatomy Project (CGAP) xProfiler and cDNA Digital Gene Expression Displayer (DGED) have been made available to the scientific community over a decade...
BMCBI
2011
12 years 11 months ago
2011
BMCBI
2011
12 years 11 months ago
2011
Background: When investigating covariate interactions and group associations with standard regression analyses, the relationship between the response variable and exposure may be ...
BMCBI
2011
12 years 11 months ago
2011
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
BMCBI
2011
12 years 11 months ago
2011
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
BMCBI
2011
12 years 11 months ago
2011
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
BMCBI
2011
12 years 11 months ago
2011
Background: Methods of determining whether or not any particular HIV-1 sequence stems - completely or in part - from some unknown HIV-1 subtype are important for the design of vac...
BMCBI
2011
12 years 11 months ago
2011
Background: Viral zoonosis, the transmission of a virus from its primary vertebrate reservoir species to humans, requires ubiquitous cellular proteins known as receptor proteins. ...
BMCBI
2011
12 years 11 months ago
2011
Background: Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assay...