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CSB
2005
IEEE
132views Bioinformatics» more  CSB 2005»
13 years 7 months ago
A Fast Shotgun Assembly Heuristic
Genome sequencing opened a new era in genetics allowing the study of genomes at the nucleotide level. However, the chosen method of sequencing produced large numbers of nucleotide...
Christopher Wilks, Sami Khuri
CSB
2005
IEEE
165views Bioinformatics» more  CSB 2005»
13 years 7 months ago
Sequential Diagonal Linear Discriminant Analysis (SeqDLDA) for Microarray Classification and Gene Identification
In microarray classification we are faced with a very large number of features and very few training samples. This is a challenge for classical Linear Discriminant Analysis (LDA),...
Roger Pique-Regi, Antonio Ortega, Shahab Asgharzad...
CSB
2005
IEEE
128views Bioinformatics» more  CSB 2005»
13 years 7 months ago
Application of a Generalized MWC Model for the Mathematical Simulation of Metabolic Pathways Regulated by Allosteric Enzymes
In our effort to elucidate the systems biology of the model organism, Escherichia coli, we have developed a mathematical model that simulates the allosteric regulation for threoni...
Tarek S. Najdi, Chin-Rang Yang, Bruce E. Shapiro, ...
CSB
2005
IEEE
233views Bioinformatics» more  CSB 2005»
13 years 7 months ago
PSIST: Indexing Protein Structures Using Suffix Trees
Feng Gao, Mohammed Javeed Zaki
CSB
2005
IEEE
147views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Accurate Prediction of Orthologous Gene Groups in Microbes
Hongwei Wu, Fenglou Mao, Victor Olman, Ying Xu
CSB
2005
IEEE
136views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Whole Genome Phylogeny Based on Clustered Signature String Composition
Peptide compositions constructed out of whole sets of protein sequences can be used as species signatures for phylogenetic analysis. To account for point mutations, an amino acid ...
Xiaomeng Wu, Guohui Lin, Xiu-Feng Wan, Dong Xu
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Discovering Functional Transcription Factor Binding from Superimposed Gene Networks
The availability of entire genome sequences, coupled with genome-wide studies of gene expression, offers promise for discovering new pathways along with their regulatory programs....
Matthew T. Weirauch, Joshua M. Stuart
CSB
2005
IEEE
145views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Classification Methods for HIV-1 Medicated Neuronal Damage
HIV-1-associated dementia (HAD) is the most devastating disease happened in the central nervous system of AIDS patients. Neuronal damage, the early indicator of HAD, under differe...
Mengjun Wang, Jialin Zheng, Zhengxin Chen, Yong Sh...
CSB
2005
IEEE
205views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Fractal Clustering for Microarray Data Analysis
DNA microarray experiments generate a substantial amount of information about global gene expression. Gene expression profiles can be represented as points in multi-dimensional sp...
Lu-Yong Wang, Ammaiappan Balasubramanian, Amit Cha...