BMCBI
2010
13 years 5 months ago
2010
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
BMCBI
2010
13 years 5 months ago
2010
Background: Comparative analysis of gene expression profiling of multiple biological categories, such as different species of organisms or different kinds of tissue, promises to e...
BMCBI
2010
13 years 5 months ago
2010
Background: Image analysis is an essential component in many biological experiments that study gene expression, cell cycle progression, and protein localization. A protocol for tr...
BMCBI
2010
13 years 5 months ago
2010
Background: Gene expression data can be analyzed by summarizing groups of individual gene expression profiles based on GO annotation information. The mean expression profile per g...
BMCBI
2010
13 years 5 months ago
2010
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
BMCBI
2010
13 years 5 months ago
2010
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
BIOINFORMATICS
2008
13 years 5 months ago
2008
Motivation: Bacterial small ribonucleic acids (sRNAs) that are not ribosomal and transfer or messenger RNAs were initially identified in the sixties whereas their molecular functi...
BMCBI
2010
13 years 5 months ago
2010
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
BMCBI
2010
13 years 5 months ago
2010
Background: There is a large amount of gene expression data that exists in the public domain. This data has been generated under a variety of experimental conditions. Unfortunatel...
BMCBI
2010
13 years 5 months ago
2010
Background: An important objective of DNA microarray-based gene expression experimentation is determining interrelationships that exist between differentially expressed genes and ...