BMCBI
2010
13 years 4 months ago
2010
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
BMCBI
2010
13 years 4 months ago
2010
Background: Probing the complex fusion of genetic and environmental interactions, metabolic profiling (or metabolomics/metabonomics), the study of small molecules involved in meta...
BMCBI
2010
13 years 4 months ago
2010
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
BIOCOMP
2009
13 years 5 months ago
2009
It is widely recognized that complexity of metabolic networks arises from duplication, recruitment and recombination of enzyme protein domains. However, variations of the domain ev...
CMSB
2003
Springer
13 years 10 months ago
2003
Springer
Metabolic flux estimation—the problem of finding out the rates of reactions in metabolic pathways—is an important problem area in the study of metabolism. The most accurate t...
GCB
2004
Springer
13 years 10 months ago
2004
Springer
: Carbon Labeling Systems (CLS) are large equation systems that describe the dynamics of labeled carbon atoms in a metabolic network. The rapid solution of these systems is the alg...
DNA
2007
Springer
13 years 11 months ago
2007
Springer
Abstract. Metabolic P systems, shortly MP systems, are a special class of P systems, introduced for expressing biological metabolism. Their dynamics are computed by metabolic algor...
CISIS
2010
IEEE
13 years 11 months ago
2010
IEEE
—This paper presents a qualitative logic-based method for the steady-state analysis and revision of metabolic networks with inhibition. The approach is able to automatically revi...