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CEC
2011
IEEE
9 years 2 months ago
Comparing alternative energy functions for the HP model of protein structure prediction
Abstract—Protein structure prediction is the problem of finding the functional conformation of a protein given only its amino uence. The HP lattice model is an abstract formulat...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...
ISBRA
2011
Springer
9 years 6 months ago
Query-Adaptive Ranking with Support Vector Machines for Protein Homology Prediction
Abstract. Protein homology prediction is a crucial step in templatebased protein structure prediction. The functions that rank the proteins in a database according to their homolog...
Yan Fu, Rong Pan, Qiang Yang, Wen Gao
BMCBI
2010
145views more  BMCBI 2010»
9 years 9 months ago
Directionality in protein fold prediction
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...
Jonathan J. Ellis, Fabien P. E. Huard, Charlotte M...
PRIB
2010
Springer
176views Bioinformatics» more  PRIB 2010»
10 years 19 days ago
An On/Off Lattice Approach to Protein Structure Prediction from Contact Maps
Abstract. An important unsolved problem in structural bioinformatics is that of protein structure prediction (PSP), the reconstruction of a biologically plausible three-dimensional...
Stefano Teso, Cristina Di Risio, Andrea Passerini,...
NAR
2007
96views more  NAR 2007»
10 years 2 months ago
DOMAC: an accurate, hybrid protein domain prediction server
Protein domain prediction is important for protein structure prediction, structure determination, function annotation, mutagenesis analysis and protein engineering. Here we descri...
Jianlin Cheng
BMCBI
2004
138views more  BMCBI 2004»
10 years 2 months ago
Constraint Logic Programming approach to protein structure prediction
Background: The protein structure prediction problem is one of the most challenging problems in biological sciences. Many approaches have been proposed using database information ...
Alessandro Dal Palù, Agostino Dovier, Feder...
ESWA
2006
122views more  ESWA 2006»
10 years 2 months ago
Transmembrane segments prediction and understanding using support vector machine and decision tree
In recent years, there have been many studies focusing on improving the accuracy of prediction of transmembrane segments, and many significant results have been achieved. In spite...
Jieyue He, Hae-Jin Hu, Robert W. Harrison, Phang C...
BMCBI
2006
129views more  BMCBI 2006»
10 years 2 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BMCBI
2006
165views more  BMCBI 2006»
10 years 2 months ago
Improving the quality of protein structure models by selecting from alignment alternatives
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thoma...
BMCBI
2010
175views more  BMCBI 2010»
10 years 2 months ago
Calibur: a tool for clustering large numbers of protein decoys
Background: Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of...
Shuai Cheng Li, Yen Kaow Ng
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