Datapath width optimization is very effective for reducing the area of a custom-made embedded system. The trivial way of optimization is to iteratively customize, evaluate, and redesign a system to reach near an optimal value. The resulting effect is a long design time. In this paper, we introduce an effective scheme that accelerates design. A system-level pruning of design exploration space speeds up the optimization process. Through a single-pass simulation for a reference customization and a model for estimating and evaluating the system’s performance, pruning of design space is achieved. Experimental results show that a substantial reduction in design time is possible. Categories and Subject Descriptors B.7.1 [Integrated Circuits]: Types and Design Styles; B.7.2 [Integrated Circuits]: Design Aids; C.3 [Specialpurpose and Application-based Systems]; C.5.4 [Integrated Circuits]: Computer System Implementation—VLSI systems; D.3.2 [Programming Languages]: Language Classificati...