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DNA
2003
Springer

A Lab-on-a-Chip Module for Bead Separation in DNA-Based Concept Learning

13 years 8 months ago
A Lab-on-a-Chip Module for Bead Separation in DNA-Based Concept Learning
Affinity separation with magnetic beads is an important and widely used technique for DNA computing. We have designed and implemented an experimental lab-on-a-chip module for affinity-bead separation for DNA-based concept learning. Magnetic beads with DNA-probe sequences immobilized on their surface were used to select target strands, and these beads are restrained in the channel by a permanent magnet on top of the module. The separation process consists of two steps, i.e. hybridization and denaturation. We confirmed the separation process by a mixed solution that contains FITC modified strands, and measured the yield by UV spectrophotometer. The experimental results demonstrate a successful separation of the mixed DNA.
Hee-Woong Lim, Hae-Man Jang, Sung-Mo Ha, Young-Gyu
Added 06 Jul 2010
Updated 06 Jul 2010
Type Conference
Year 2003
Where DNA
Authors Hee-Woong Lim, Hae-Man Jang, Sung-Mo Ha, Young-Gyu Chai, Suk-In Yoo, Byoung-Tak Zhang
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