PDA: Pooled DNA analyzer

12 years 9 months ago
PDA: Pooled DNA analyzer
Background: Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring possible genetic diversity. Genotyping large numbers of SNPs individually is performed routinely but is cost prohibitive for large-scale genetic studies. DNA pooling is a reliable and cost-saving alternative genotyping method. However, no software has been developed for complete pooled-DNA analyses, including data standardization, allele frequency estimation, and single/multipoint DNA pooling association tests. This motivated the development of the software, 'PDA' (Pooled DNA Analyzer), to analyze pooled DNA data. Results: We develop the software, PDA, for the analysis of pooled-DNA data. PDA is originally implemented with the MATLAB
Hsin-Chou Yang, Chia-Ching Pan, Chin-Yu Lin, Cathy
Added 10 Dec 2010
Updated 10 Dec 2010
Type Journal
Year 2006
Authors Hsin-Chou Yang, Chia-Ching Pan, Chin-Yu Lin, Cathy S. J. Fann
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