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BMCBI
2007
97views more  BMCBI 2007»
14 years 9 months ago
A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
Francisco Llaneras, Jesús Picó
BMCBI
2008
128views more  BMCBI 2008»
14 years 9 months ago
Efficient computation of absent words in genomic sequences
Background: Analysis of sequence composition is a routine task in genome research. Organisms are characterized by their base composition, dinucleotide relative abundance, codon us...
Julia Herold, Stefan Kurtz, Robert Giegerich
BMCBI
2007
124views more  BMCBI 2007»
14 years 9 months ago
Analysis on multi-domain cooperation for predicting protein-protein interactions
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Rui-Sheng Wang, Yong Wang, Ling-Yun Wu, Xiang-Sun ...
BMCBI
2007
86views more  BMCBI 2007»
14 years 9 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
BMCBI
2008
242views more  BMCBI 2008»
14 years 9 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
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