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BMCBI
2007
146views more  BMCBI 2007»
14 years 11 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
JCB
2006
185views more  JCB 2006»
14 years 11 months ago
A Probabilistic Methodology for Integrating Knowledge and Experiments on Biological Networks
Biological systems are traditionally studied by focusing on a specific subsystem, building an intuitive model for it, and refining the model using results from carefully designed ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...
BMCBI
2010
165views more  BMCBI 2010»
14 years 11 months ago
Bayesian integrated modeling of expression data: a case study on RhoG
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
Rashi Gupta, Dario Greco, Petri Auvinen, Elja Arja...
RECOMB
2008
Springer
15 years 12 months ago
A Bayesian Approach to Protein Inference Problem in Shotgun Proteomics
The protein inference problem represents a major challenge in shotgun proteomics. Here we describe a novel Bayesian approach to address this challenge that incorporates the predict...
Yong Fuga Li, Randy J. Arnold, Yixue Li, Predrag R...
ITRE
2005
IEEE
15 years 5 months ago
Structure learning of Bayesian networks using a semantic genetic algorithm-based approach
A Bayesian network model is a popular technique for data mining due to its intuitive interpretation. This paper presents a semantic genetic algorithm (SGA) to learn a complete qual...
Sachin Shetty, Min Song