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BMCBI
2007
154views more  BMCBI 2007»
14 years 10 months ago
Bounds on the distribution of the number of gaps when circles and lines are covered by fragments: Theory and practical applicati
Background: The question of how a circle or line segment becomes covered when random arcs are marked off has arisen repeatedly in bioinformatics. The number of uncovered gaps is o...
John Moriarty, Julian R. Marchesi, Anthony Metcalf...
BMCBI
2007
133views more  BMCBI 2007»
14 years 10 months ago
MATLIGN: a motif clustering, comparison and matching tool
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...
Matti Kankainen, Ari Löytynoja
BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
High-throughput bioinformatics with the Cyrille2 pipeline system
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
BMCBI
2008
124views more  BMCBI 2008»
14 years 9 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
BMCBI
2008
83views more  BMCBI 2008»
14 years 9 months ago
Models of deletion for visualizing bacterial variation: an application to tuberculosis spoligotypes
Background: Molecular typing methods are commonly used to study genetic relationships among bacterial isolates. Many of these methods have become standardized and produce portable...
Josephine F. Reyes, Andrew R. Francis, Mark M. Tan...