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BMCBI
2008
118views more  BMCBI 2008»
15 years 4 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
JCB
2007
144views more  JCB 2007»
15 years 3 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
ECCV
2010
Springer
15 years 8 months ago
Discriminative Mixture-of-Templates for Viewpoint Classification
Abstract. Object viewpoint classification aims at predicting an approximate 3D pose of objects in a scene and is receiving increasing attention. State-of-the-art approaches to view...
COLT
2008
Springer
15 years 5 months ago
Extracting Certainty from Uncertainty: Regret Bounded by Variation in Costs
Prediction from expert advice is a fundamental problem in machine learning. A major pillar of the field is the existence of learning algorithms whose average loss approaches that ...
Elad Hazan, Satyen Kale
BMCBI
2011
14 years 7 months ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...