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BMCBI
2007
119views more  BMCBI 2007»
14 years 11 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
BMCBI
2010
131views more  BMCBI 2010»
14 years 11 months ago
JISTIC: Identification of Significant Targets in Cancer
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
Felix Sanchez-Garcia, Uri David Akavia, Eyal Mozes...
STOC
2007
ACM
134views Algorithms» more  STOC 2007»
15 years 12 months ago
Hardness of routing with congestion in directed graphs
Given as input a directed graph on N vertices and a set of source-destination pairs, we study the problem of routing the maximum possible number of source-destination pairs on pat...
Julia Chuzhoy, Venkatesan Guruswami, Sanjeev Khann...
BMCBI
2010
115views more  BMCBI 2010»
14 years 11 months ago
Assessment and optimisation of normalisation methods for dual-colour antibody microarrays
Background: Recent advances in antibody microarray technology have made it possible to measure the expression of hundreds of proteins simultaneously in a competitive dual-colour a...
Martin Sill, Christoph Schroder, Jörg D. Hohe...
CIDM
2009
IEEE
15 years 6 months ago
Ensemble member selection using multi-objective optimization
— Both theory and a wealth of empirical studies have established that ensembles are more accurate than single predictive models. Unfortunately, the problem of how to maximize ens...
Tuve Löfström, Ulf Johansson, Henrik Bos...