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    BMCBI
    2006
    145views more  BMCBI 2006»
    GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
    13 years 6 months ago
    GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
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    Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
    Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
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    BMCBI
    2006
    156views more  BMCBI 2006»
    Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
    13 years 6 months ago
    Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
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    Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
    Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
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    BMCBI
    2006
    127views more  BMCBI 2006»
    Using local gene expression similarities to discover regulatory binding site modules
    13 years 6 months ago
    Using local gene expression similarities to discover regulatory binding site modules
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    Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
    Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
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    BMCBI
    2004
    169views more  BMCBI 2004»
    A power law global error model for the identification of differentially expressed genes in microarray data
    13 years 6 months ago
    A power law global error model for the identification of differentially expressed genes in microarray data
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    Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
    Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...
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    BMCBI
    2011
    179views Artificial Intelligence» more  BMCBI 2011»
    In-silico prediction of disorder content using hybrid sequence representation
    12 years 9 months ago
    In-silico prediction of disorder content using hybrid sequence representation
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    Background: Intrinsically disordered proteins play important roles in various cellular activities and their prevalence was implicated in a number of human diseases. The knowledge ...
    Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou...
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